Why the study?
Does comorbid depression increase all-cause and cardiovascular mortality in people with diabetes?
Population
16 longitudinal studies pooling 109,046 individuals with diabetes mellitus, mean age ranging from 62 to 76…
Comparison
Presence of comorbid depression at baseline. vs Absence of depression at baseline.
Design
Meta-analysis
Follow-up
mean 6 years (range 2-10 years)
Authors
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Warrants depression screening in diabetes risk assessment; extends observational mortality data but leaves causal effects open.
Does comorbid depression increase all-cause and cardiovascular mortality in people with diabetes?
Comorbid depression in patients with diabetes is associated with an approximately 1.5-fold increased risk of both all-cause and cardiovascular mortality.
Dooren et al. (2013) studied this question.
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