Comparison of Clinical profile and outcome between young (≤45yrs) male and female patients with coronary artery disease undergoing percutaneous coronary intervention, a single center study

Background -There is scarcity of data regarding CAD and the outcome following PCI in young south Indian population. We sought to analyze the clinical, coronary angiographic features and outcome in young adults(45 years of age) with CAD who underwent PCI and also to compare that between young male and female patients . Methods-Angiographic and clinical data from total 150 patients aged 45 years of which, 110 male patients who underwent PCI from January 2014 to January 2016 were compared to age-matched 40 female patients in our centre . All patients were treated according to guidelines. 1, 6 and 12 months clinical follow-up were performed in all patients. Coronary angiography was performed only if patients were symptomatic or TMT positive. Results -CAD risk factors were more prevalent in young male patients, Diabetes mellitus was found in 32. 72%, hypertension (34.54%), dyslipidemia (36.36%), smoking (38.18%), tobacco consumption (21.81%) and hyperhomocysteinemia (23.63%) as compared to female group (17.5%,20%,12.5%,0%,5%,12.5% respectively). Family history of CAD was found to be higher in female patients as compared to males (40% vs 6.36%; p =0.000). Single vessel disease was found to be common among female patients(60% vs 40.92%) and www.jmscr.igmpublication.org