Key result
Moderate dietary sodium restriction increased the blood pressure-lowering effect of carvedilol.
Why the study?
Does moderate sodium restriction increase the antihypertensive effect of carvedilol in patients?
Population
19 patients
Comparison
Moderate sodium restriction combined with… vs Carvedilol without sodium restriction
Design
RCT, randomly allocated, double-blind
Authors
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Supports counseling on moderate sodium restriction with carvedilol; extends RCT evidence for diet-drug synergy in hypertension.
Does moderate sodium restriction increase the antihypertensive effect of carvedilol in patients?
Moderate sodium restriction enhances the blood pressure-lowering effect of carvedilol.
Ruilope et al. (1993) studied this question. Moderate dietary sodium restriction increased the blood pressure-lowering effect of carvedilol.
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