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July 1, 1968The Journal of Cell BiologyOpen Access

The Ultrastructure of the M Line in Skeletal Muscle

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Population

Fibers from frog nonglycerinated semitendinosus muscles

Design

Preclinical

Authors

GKG. G. KnappeisUniversity of CopenhagenFCF. CarlsenUniversity of Copenhagen

Discussion

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Overview

Structural details of the M line in animal fibers extend ultrastructural models; clinical relevance to human sarcomere disorders remains untested.

Structured PICO

P
Population
Fibers from frog nonglycerinated semitendinosus muscles
I
Intervention
Electron microscopy at body length and at different degrees of shortening and stretch
O
Outcome
Ultrastructure of the M line

Provides a structural model for the M line in skeletal muscle, detailing its composition of M bridges and M filaments and its behavior during stretch and shortening.

Cite This Study

Knappeis et al. (1968) studied this question.

synapsesocial.com/papers/6a102abc2badbc352aff72f6https://doi.org/10.1083/jcb.38.1.202
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