Key result
Single-particle analysis of the M-region of myosin filaments from goldfish skeletal muscle revealed the three-dimensional structure and density distribution to about 55 Å resolution.
Population
Myosin filaments from goldfish skeletal muscle
Design
Preclinical
Authors
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Advances vertebrate myosin filament structural insights; leaves open extension to mammalian cardiac muscle and clinical relevance.
This study provides the first single-particle 3D reconstruction of isolated M-regions of vertebrate striated muscle myosin filaments, revealing structural details at 55 Å resolution.
AL-Khayat et al. (2010) studied this question. Single-particle analysis was evaluated on Three-dimensional structure and density distribution to about 55 Å resolution. Single-particle analysis of the M-region of myosin filaments from goldfish skeletal muscle revealed the three-dimensional structure and density distribution to about 55 Å resolution.
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