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September 4, 2013JACC. Cardiovascular imagingOpen Access

T1 Mapping for the Diagnosis of Acute Myocarditis Using CMR

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Why the study?

Does native T1 mapping provide superior diagnostic performance for acute myocarditis compared to T2W-CMR and LGE imaging in patients with suspected acute myocarditis?

Population

95 individuals, comprising 50 patients with suspected acute myocarditis and 45 controls.

Comparison

Native T1 mapping using 1.5-T cardiac magnetic… vs Dark-blood T2-weighted-CMR, bright-blood…

Design

Case-control

Authors

VFVanessa M. FerreiraCardiac ImagingSPStefan K. PiechnikCardiac ImagingEDErica Dall’ArmellinaUniversity of Leeds

Discussion

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Implication

May support non-contrast diagnosis in suspected myocarditis; leaves open prospective validation versus T2W-CMR and LGE.

Structured PICO

Does native T1 mapping provide superior diagnostic performance for acute myocarditis compared to T2W-CMR and LGE imaging in patients with suspected acute myocarditis?

P
Population
95 individuals, comprising 50 patients with suspected acute myocarditis (mean age 42 ± 16 years, 22% women) and 45 controls (mean age 42 ± 14 years, 22% women).
I
Intervention
Native T1 mapping (shortened modified look-locker inversion recovery) using 1.5-T cardiac magnetic resonance (CMR)
C
Comparator
Dark-blood T2-weighted (T2W)-CMR, bright-blood T2W-CMR, and late gadolinium enhancement (LGE) imaging
O
Outcome
Diagnostic performance (area under the curve, sensitivity, specificity, and diagnostic accuracy) for detecting acute myocarditissurrogate

Native T1 mapping offers excellent diagnostic performance for acute myocarditis, superior to T2-weighted CMR and comparable to LGE, making it a valuable tool especially when gadolinium contrast is contraindicated.

Cite This Study

Ferreira et al. (2013) studied this question.

synapsesocial.com/papers/6a102e6692676d5461fdad2bhttps://doi.org/10.1016/j.jcmg.2013.03.008

Topics

Cardiac MRIMyocarditis
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Also Consider

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  1. 1"Black blood" T2-weighted inversion-recovery MR imaging of the heart.1996 · 567 citations
  2. 2Cardiovascular magnetic resonance by non contrast T1-mapping allows assessment of severity of injury in acute myocardial infarction2012 · 284 citations
  3. 3Diagnostic Performance of Cardiovascular Magnetic Resonance in Patients With Suspected Acute Myocarditis2005 · 775 citations
  4. 4Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper2009 · 2,527 citations
  5. 5Bright-Blood T2-Weighted MRI Has Higher Diagnostic Accuracy Than Dark-Blood Short Tau Inversion Recovery MRI for Detection of Acute Myocardial Infarction and for Assessment of the Ischemic Area at Risk and Myocardial Salvage2011 · 112 citations