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March 16, 2023Open Access

Prevalence of Elevated Blood Pressure and Left Ventricular Hypertrophy in Adolescents with Congenital Heart Disease

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Why the study?

Data on the prevalence of elevated blood pressure in youths with CHD were limited, motivating this study to determine the prevalence of elevated BP and LVH in adolescents with CHD.

Population

855 patients with biventricular CHD aged 13-17 years

Comparison

Normotensive vs Elevated BP vs Stage 1 HTN vs Stage 2 HTN

Design

Retrospective echocardiographic study

Authors

AWAaron T. WalshLe Bonheur Children's HospitalKHKan N. HorNationwide Children's HospitalMEMariah EisnerNationwide Children's Hospital

Discussion

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Implication

Supports BP monitoring in adolescents with congenital heart disease; hypothesis-generating and needs prospective validation.

Structured PICO

P
Population
855 adolescents (aged 13-17 years) with biventricular congenital heart disease (excluding single ventricular lesions), mean age 15.5, 56.7% male, US-based. Key inclusion: documented BP, height, weight, and measurement of LVMI-ht2.7.
O
Outcome
Prevalence of elevated blood pressure and left ventricular hypertrophy (defined as LVMI-ht2.7 ≥ 38.6 g/ht2.7)surrogate

Adolescents with biventricular congenital heart disease have a high prevalence of elevated blood pressure and left ventricular hypertrophy, with BMI being a significant risk factor, highlighting the need for early screening.

Limitations

  • Single center retrospective cohort study
  • Inability to determine causation
  • Did not stratify by types of CHD
  • Single time-point blood pressures were utilized
  • Whether patients were identified as hypertensive or if they were being actively treated for HTN was not investigated

Cite This Study

Walsh et al. (2023) studied this question.

synapsesocial.com/papers/6a1036392badbc352aff8a0ahttps://doi.org/10.1101/2023.03.15.23287130

Topics

Congenital heart disease adultsHypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Impact of Obesity and Body Fat Distribution on Ambulatory Blood Pressure in Children and Adolescents1998 · 113 citations
  2. 2Long term results (15-30 years) of surgical repair of aortic coarctation.1987 · 244 citations
  3. 3Association of Blood Pressure Level With Left Ventricular Mass in Adolescents2019 · 124 citations
  4. 4Relation of obesity and gender to left ventricular hypertrophy in normotensive and hypertensive adults.1994 · 395 citations
  5. 5Progression of Normotensive Adolescents to Hypertensive Adults2010 · 149 citations