Key result
Targeting myocardial fibrosis with specific antihypertensive agents, such as angiotensin II inhibitors, offers a promising new approach for the management of hypertensive heart disease.
Management of hypertensive heart disease should evolve beyond blood pressure control and LVH regression to include the noninvasive assessment and targeted pharmacological reversal of myocardial fibrosis.
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May support fibrosis-targeted antihypertensives in hypertensive heart disease; leaves open randomized outcome trials before practice change.
González et al. (2005) conducted a review in hypertensive heart disease. Targeting myocardial fibrosis with specific antihypertensive agents, such as angiotensin II inhibitors, offers a promising new approach for the management of hypertensive heart disease.
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