Why the study?
Does lovastatin added to a Step 1 diet reduce myocardial ischemia in patients with coronary artery disease and elevated cholesterol?
Population
n=40 patients with proven coronary artery disease, total serum cholesterol between 191 and 327 mg/dL, and at…
Comparison
Lovastatin added to an American Heart… vs Placebo added to an American Heart Association…
Design
RCT, randomized
Follow-up
4 to 6 months
Authors
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Supports adding lovastatin to diet for ischemia reduction in CAD with elevated cholesterol; extends lipid-lowering evidence to daily ischemic burden.
Does lovastatin added to a Step 1 diet reduce myocardial ischemia in patients with coronary artery disease and elevated cholesterol?
Cholesterol lowering with lovastatin significantly reduces or eliminates episodes of myocardial ischemia during daily life in patients with coronary artery disease.
Andrews et al. (1997) studied this question.
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