January 9, 2006Archives of Internal Medicine
10-Year Follow-up of Subclinical Cardiovascular Disease and Risk of Coronary Heart Disease in the Cardiovascular Health Study
Why the study?
Does the presence of subclinical cardiovascular disease predict the incidence of coronary heart disease in individuals 65 years or older without clinical cardiovascular disease?
Population
Individuals 65 years or older without clinical cardiovascular disease at baseline from the Cardiovascular…
Comparison
Presence of subclinical cardiovascular disease… vs Absence of subclinical cardiovascular disease at…
Design
Cohort
Follow-up
10 years
Authors
Discussion
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Member takes
Implication
May inform CHD risk stratification in older adults; hypothesis-generating and requires prospective validation before clinical adoption.
Structured PICO
Does the presence of subclinical cardiovascular disease predict the incidence of coronary heart disease in individuals 65 years or older without clinical cardiovascular disease?
P
Population
Individuals 65 years or older without clinical cardiovascular disease at baseline from the Cardiovascular Health Study
I
Intervention
Presence of subclinical cardiovascular disease at baseline
C
Comparator
Absence of subclinical cardiovascular disease at baseline
O
Outcome
Incidence of coronary heart disease (CHD)hard clinical
Subclinical cardiovascular disease is highly prevalent in older adults and independently predicts the 10-year risk of incident coronary heart disease, particularly in those with hypertension or diabetes.
Cite This Study
Lewis H. Kuller (2006) studied this question.