Key result
Subclinical cardiovascular disease was associated with a decline in successful aging equivalent to 6.5 (95% CI 6.4-6.6) years of aging for women and 5.6 (95% CI 5.4-5.8) years for men.
Why the study?
Does subclinical cardiovascular disease reduce the likelihood of successful aging in adults aged 65 years and older?
Cohort (n=2,932)
Does subclinical cardiovascular disease reduce the likelihood of successful aging in adults aged 65 years and older?
Effect estimate: Equivalent years of aging: 6.5 (women), 5.6 (men) (95% CI 6.4-6.6 (women), 5.4-5.8 (men))
Subclinical cardiovascular disease significantly reduces the likelihood of successful aging, accelerating functional decline equivalent to approximately 6 years of aging.
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May inform risk stratification in older adults; leaves open whether treating subclinical CVD preserves successful aging.
Anne B. Newman (2003) conducted a cohort in Subclinical cardiovascular disease (n=2,932). Subclinical cardiovascular disease vs. No subclinical vascular disease was evaluated on Successful aging (remaining free of cardiovascular disease, cancer, and chronic obstructive pulmonary disease and with intact physical and cognitive functioning) (Equivalent years of aging: 6.5 (women), 5.6 (men), 95% CI 6.4-6.6 (women), 5.4-5.8 (men)). Subclinical cardiovascular disease was associated with a decline in successful aging equivalent to 6.5 (95% CI 6.4-6.6) years of aging for women and 5.6 (95% CI 5.4-5.8) years for men.
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