Why the study?
Compared with valve replacement, aortic valve repair for rare unicuspid aortic valve defects offers a potential strategy to achieve lower valve-related events and enhanced quality of life.
Does bicuspidization using the pericardial advancement technique prevent aortic regurgitation or significant stenosis in patients with unicuspid aortic valve?
Does bicuspidization using the pericardial advancement technique prevent aortic regurgitation or significant stenosis in patients with unicuspid aortic valve?
Bicuspidization of the unicuspid aortic valve using the pericardial advancement technique appears to be a feasible repair strategy with good mid-term valve function.
Supports pericardial bicuspidization in select unicuspid aortic valve cases; leaves open durability and generalizability questions for prospective trials.
Unicuspid aortic valve (UAV) is a rare congenital defect. Compared with valve replacement, aortic valve repair is a better potential strategy to achieve a low rate of valve-related events and an enhanced quality of life. We herein report two cases of aortic valve repair for UAV accompanied by aneurysm of the ascending aorta. By retaining the free margin tissue and forming a neocommissure to the side of the left lateral commissure that is 180 degrees opposite and the same height, we were able to achieve bicuspidization of the UAV. A glutaraldehyde-treated autologous pericardium patch was placed along the cusp connection to the annulus to expand the aortic cusp. During the follow-up period of over 4 years, the patients showed no signs of aortic regurgitation or significant stenosis.
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Munakata et al. (2025) studied this question.
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