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The aim is to report on the progress of curating conserved domain models within the NCBI's CDD.

December 17, 2004Nucleic Acids ResearchOpen Access

CDD: a Conserved Domain Database for protein classification

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The aim is to report on the progress of curating conserved domain models within the NCBI's CDD.
Utilized CD-Search to identify conserved domains in protein sequences.
Linked CDD with other Entrez databases like Proteins and Taxonomy.
Analyzed updates to the curation efforts and improvements in information retrieval.
Improvements in functionality of CDD's information retrieval system were documented.
Enhanced performance in mapping protein sequences to domain models was achieved.
CD-Search results provide direct links to curated domain hierarchies.

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Randomized trial assesses protein classification improvements in NCBI's CDD, indicating enhanced functionality.

Aron Marchler‐Bauer (2004) studied this question.

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