Key result
Physical training promotes increased myocardial capillary density in animal models, but studies in patients with coronary artery disease have generally failed to show increased coronary blood flow.
Why the study?
Does physical training improve myocardial vascularity and perfusion in experimental models and humans?
Population
Experimental animals (dogs, pigs, rats), athletes, and patients with coronary artery disease
Comparison
Physical training vs Untrained animals or sedentary persons
Design
Review
Authors
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No support for coronary perfusion gains with training in CAD; leaves open need for sensitive human imaging studies.
Does physical training improve myocardial vascularity and perfusion in experimental models and humans?
While animal models suggest physical training enhances myocardial vascularity and collateral flow, evidence in human patients with coronary artery disease remains inconclusive, warranting further investigation with more sensitive techniques.
J. Scheuer (1982) conducted a review in Coronary artery disease. Physical training vs. Untrained state / Sedentary persons was evaluated on Myocardial vascularity and perfusion. Physical training promotes increased myocardial capillary density in animal models, but studies in patients with coronary artery disease have generally failed to show increased coronary blood flow.
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