Why the study?
Previous studies evaluating the association between handgrip strength and hypertension risk utilized cross-sectional designs, leaving prospective evidence lacking.
Does higher normalized handgrip strength reduce the future risk of hypertension in older adults?
Does higher normalized handgrip strength reduce the future risk of hypertension in older adults?
In a prospective cohort of older Finnish adults, higher normalized handgrip strength was not significantly associated with a reduced risk of future hypertension, suggesting previous cross-sectional associations may have been driven by study design limitations.
Higher normalized handgrip strength was not associated with reduced hypertension risk; challenges prior cross-sectional reports and leaves the longitudinal relationship open.
Previous reports of an association between handgrip strength (HGS) and the risk of hypertension have utilized cross-sectional designs. We aimed to assess the prospective association between HGS and hypertension risk in a general population. Handgrip strength was assessed at baseline in 463 Finnish men and women aged 61-73 years. Handgrip strength was normalized (HGS/body weight2/3). After 16 years median follow-up, 110 hypertension cases occurred. Comparing the extreme tertiles of normalized HGS, the multivariable adjusted hazard ratio (95% CI) for hypertension was 0.63 (0.38–1.04). Previous evidence of associations may have been driven by study design limitations such as lack of temporality.
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Kunutsor et al. (2021) studied this question.
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