Why the study?
Does acute intravenous ascorbic acid infusion improve carotid artery compliance in sedentary postmenopausal women compared to habitually exercising postmenopausal women?
Population
26 healthy postmenopausal women, comprising sedentary and endurance exercise-trained individuals.
Comparison
Acute intravenous infusion of supraphysiological… vs Acute intravenous infusion of saline (control).
Design
Cross-sectional
Follow-up
Acute (during infusion)
Authors
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May improve carotid compliance selectively in sedentary postmenopausal women; hypothesis-generating and should not yet change practice.
Does acute intravenous ascorbic acid infusion improve carotid artery compliance in sedentary postmenopausal women compared to habitually exercising postmenopausal women?
Acute antioxidant administration abolishes the difference in large elastic artery compliance between sedentary and exercising postmenopausal women, suggesting oxidative stress mediates the reduced compliance in sedentary individuals.
Moreau et al. (2006) studied this question.
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