Population
Canine left ventricle model of myocardial infarction (isotropic, initially spherical, membrane model)
Design
Preclinical
Authors
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Requires human validation before clinical consideration; extends computational modeling of post-infarct compensation in canines.
A computational model of the canine left ventricle suggests that normal cardiac output can be maintained for acute infarcts up to 41% of the ventricular surface, with moderately stiff infarcts preserving function better than extensible ones.
Bogen et al. (1980) studied this question.
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