Why the study?
Racial disparities persist in TAVR utilization, prompting an evaluation of whether procedure-related adverse outcomes represent barriers to TAVR use among African Americans.
Are there racial disparities in the utilization and adverse outcomes of TAVR and SAVR between African American and Caucasian patients?
Are there racial disparities in the utilization and adverse outcomes of TAVR and SAVR between African American and Caucasian patients?
Despite significant racial disparities in TAVR utilization, adverse outcomes following TAVR are generally comparable between African Americans and Caucasians, suggesting outcomes should not be a barrier to TAVR use in eligible African Americans.
Highlights a need for targeted periprocedural neurologic monitoring in African American patients; extends known utilization.
Transcatheter aortic valve replacement (TAVR) has emerged as a minimally invasive alternative to surgical aortic valve replacement (SAVR). However, racial disparities in the utilization of TAVR persist. This meta-analysis attempts to determine whether the prevalence of adverse outcomes (procedure-related complications) represent barriers to the use of TAVR among African Americans (AA). The TAVR cohort consisted of 89.6% Caucasian (C) and 4.7% AA, while the SAVR cohort included 86.9% C and 6.4% AA. The utilization rate (UR) of TAVR was 1.48 and .35 among C and AA, respectively, while the UR of SAVR was 1.44 and .48 among C and AA, respectively. Following TAVR, for AA the odds ratio (OR) was greater for stroke (OR = 1.22, P = .02) and transient ischemic attack (TIA) (OR = 1.57, P < .001) and lower for undergoing the insertion of a permanent pacemaker (OR = .81, P < .001). While there was a significant difference between C and AA in TAVR and SAVR utilization, outcomes between groups following TAVR are comparable; therefore, adverse outcomes do not appear to be a barrier to the use of TAVR among eligible AA.
No takes yet. Share an insight, caveat, or question.
Kulkarni et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: