Key result
Black race is linked to ~38% lower in-hospital TAVR mortality compared to white patients.
Why the study?
Racial and ethnic disparities in the delivery of TAVR and differences in in-hospital outcomes and utilization by ethnicity remained to be determined.
Does non-white race/ethnicity impact in-hospital mortality and utilization in adult patients undergoing TAVR compared to white patients?
Observational (n=58,174)
Yes
Does non-white race/ethnicity impact in-hospital mortality and utilization in adult patients undergoing TAVR compared to white patients?
Odds Ratio: 0.62 (95% CI 0.44–0.81)
Absolute Event Rate: 2.8% vs 3.6%
p-value: p=< 0.001
While TAVR utilization increased across all races from 2011 to 2015, significant racial disparities in in-hospital mortality persist, with higher mortality observed in Hispanic and Native American patients compared to White patients.
Racial differences in TAVR mortality should not change practice; Level 5 data leaves open questions of bias, mechanisms, and equity.
AIM: We sought to determine the racial and ethnical disparities in the delivery of TAVR and to evaluate the in-hospital outcomes and utilization of TAVR stratified by patient ethnicity. METHOD: Using a national inpatient sample database between 2011 and 2015, we identified all adult patients who had TAVR. Races were identified and white race was set as control. Multiple logistic regression analysis was performed for the primary outcome of in-hospital mortality. RESULTS: Out of 58 174 patients who underwent TAVR, 50 809 (87.3%) were white, 2327 (4.0%) were black, 2311 (4.0%) were Hispanic, 640 (1.1%) Asian, 105 (0.2%) Native American and 1982 (3.4%) of other ethnicities. We found a statistically significant linear uptrend in the utilization of TAVR in patients of all races between the years 2011 and 2015. White, black, Hispanic and Native American patients had a downward linear trend for mortality during the studied years (P ≤ 0.005 for all). Black patients had lower in-hospital mortality [2.8 vs. 3.6%, odds ratio (OR) = 0.62; 95% confidence interval (CI) 0.44, 0.81 P < 0.001] compared with white patients, whereas Hispanic patients and Native Americans had higher in-hospital mortality compared with white patients (4.5% OR 1.26; 95% CI 1.01, 1.56 P = 0.041), (9.5% OR 4.44; 95% CI 2.25, 8.77 P < 0.001), respectively. CONCLUSION: Overall, TAVR utilization is associated with lower mortality. There is a rising trend in utilization of TAVR in the black population with a significantly favorable mortality trend compared with the white population.
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Ullah et al. (2021) conducted an observational in Transcatheter aortic valve replacement (n=58,174). Black race vs. White race was evaluated on in-hospital mortality (OR 0.62, 95% CI 0.44, 0.81, p=< 0.001). Black patients undergoing TAVR had lower in-hospital mortality than white patients (2.8% vs 3.6%; OR 0.62; 95% CI 0.44-0.81; P<0.001), while Hispanic and Native Americans had higher mortality.
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