Why the study?
Does a single high-fat meal impair endothelial function?
Does a single high-fat meal impair endothelial function?
High-fat meals may acutely impair endothelial function, highlighting a potential mechanism for dietary impact on atherosclerosis.
Two recent studies on the effects of single high-fat meals on endothelial function have postulated an additional mechanism by which dietary lipids can impact atherosclerosis. These studies found that dietary lipids decrease the ability of blood vessels to dilate and that this modification of endothelial function was protected by dietary antioxidants. Although this research presents an interesting hypothesis, much more research is necessary to determine the importance of dietary factors on vasoactivity.
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Tomaino et al. (2009) studied this question.
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