Does Vitamin C improve endothelial function of conduit arteries in patients with chronic heart failure?
Vitamin C improves endothelial function in patients with chronic heart failure by increasing nitric oxide availability, suggesting a role for radical-mediated nitric oxide degradation in CHF endothelial dysfunction.
Vitamin C improves FDD in patients with CHF as the result of increased availability of nitric oxide. This observation supports the concept that endothelial dysfunction in patients with CHF is, at least in part, due to accelerated degradation of nitric oxide by radicals.
Hornig et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: