Key result
Obstructive sleep apnoea syndrome is independently associated with cardiovascular disease, driven by multifactorial mechanisms including sympathetic overactivity and endothelial dysfunction.
Why the study?
Is obstructive sleep apnoea syndrome an independent risk factor for cardiovascular disease?
Is obstructive sleep apnoea syndrome an independent risk factor for cardiovascular disease?
Obstructive sleep apnoea syndrome is an independent risk factor for cardiovascular disease, necessitating large-scale collaborative and translational studies to further elucidate underlying mechanisms and identify novel therapeutic strategies.
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Cautions against practice change from observational synthesis alone; leaves open causal mechanisms and therapies for large-scale trials.
McNicholas et al. (2006) conducted a review in Obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease. Obstructive sleep apnoea syndrome is independently associated with cardiovascular disease, driven by multifactorial mechanisms including sympathetic overactivity and endothelial dysfunction.
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