Key result
Comprehensive HFpEF diagnosis requires evaluating the strengths and weaknesses of biomarkers, imaging, and invasive tests.
Why the study?
Diagnosing HFpEF can be challenging and may require multiple tests with limited availability, making guidance on the strengths and weaknesses of various diagnostic tools needed to ensure prompt and accurate diagnosis.
This review provides guidance on the comprehensive diagnostic workup for patients with suspected HFpEF, emphasizing the strengths and weaknesses of various diagnostic modalities.
May guide test selection in suspected HFpEF; leaves open prospective validation of integrated algorithms.
Diagnosis of heart failure with preserved ejection fraction (HFpEF) can be challenging and it could require different tests, some of which are affected by limited availability. Nowadays, considering that new therapies are available for HFpEF and related conditions, a prompt and correct diagnosis is relevant. However, the diagnostic role of biomarker level, imaging tools, score-based algorithms and invasive evaluation, should be based on the strengths and weaknesses of each test. The aim of this review is to help the clinician in diagnosing HFpEF, overcoming the diagnostic uncertainty and disentangling among the different underlying causes, in order to properly treat this kind of patient.
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Albani et al. (2023) conducted a review in Heart failure with preserved ejection fraction (HFpEF). Comprehensive diagnostic workup was evaluated. A comprehensive diagnostic workup for suspected heart failure with preserved ejection fraction requires evaluating the strengths and weaknesses of biomarkers, imaging, and invasive tests.
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