Key result
Simulated night shift work significantly increased the amplitude of the 24-hour circadian rhythm in heart rate compared to day shift work (3.0 vs 1.0 bpm), though sleep and physical activity were the dominant drivers of cardiac autonomic activity.
Why the study?
Does simulated night work alter heart rate and heart rate variability in human subjects?
Population
29 subjects participating in in-laboratory simulated shift work studies
Design
Other
Authors
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Night shift simulation alters HR rhythm amplitude; leaves open whether displaced sleep/activity confounds HR/HRV as CV risk markers in real-world shift work.
Does simulated night work alter heart rate and heart rate variability in human subjects?
Absolute Event Rate: 3% vs 1%
p-value: p=<0.001
Time of day, sleep/wake state, and physical activity have complex, interacting effects on cardiac autonomic activity during shift work, which must be considered when using HR and HRV as cardiovascular risk markers.
Skornyakov et al. (2018) studied Healthy young adults (simulated shift work) (n=29). Simulated night shift work vs. Simulated day shift work was evaluated on Amplitude of 24-h rhythm in heart rate (HR) (p=<0.001). Simulated night shift work significantly increased the amplitude of the 24-hour circadian rhythm in heart rate compared to day shift work (3.0 vs 1.0 bpm), though sleep and physical activity were the dominant drivers of cardiac autonomic activity.
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