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October 1, 2009Journal of Neuroimaging

Consensus Conference on Intracranial Atherosclerotic Disease: Rationale, Methodology, and Results

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Structured PICO

P

Population

Patients with intracranial atherosclerotic disease (ICAD), including those who have had a stroke or transient ischemic attack (TIA) attributed to stenosis (50-99%) of a major intracranial artery.

I

Intervention

Standardized management including antithrombotic medications (aspirin, aspirin+extended release dipyridamole, clopidogrel), aggressive atherogenic risk factor management, and intracranial angioplasty with or without stent placement.

This consensus statement provides a standardized template for the medical and interventional management of intracranial atherosclerotic disease and outlines future research priorities.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Standardizes ICAD care favoring antiplatelets and selective stenting; extends prior evidence by defining research priorities.

Cite This Study

Qureshi et al. (2009) studied this question.

synapsesocial.com/papers/6a10bc0949545a83bbee4235 https://doi.org/10.1111/j.1552-6569.2009.00414.x

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Dose-Finding, Safety, and Tolerability Study of an Oral Platelet Glycoprotein IIb/IIIa Inhibitor, Lotrafiban, in Patients With Coronary or Cerebral Atherosclerotic DiseaseRCT · 2000 · 35 citations
2Qualitative Research: Consensus methods for medical and health services researchMeta-Analysis · 1995 · 3,563 citations
3Stroke-free Survival and Its Determinants in Patients with Symptomatic Vertebrobasilar Stenosis: A Multicenter StudyCohort Study · 2003 · 141 citations
4Comparison of Primary Angioplasty With Stent Placement for Treating Symptomatic Intracranial Atherosclerotic DiseasesRetrospective Study · 2008 · 81 citations
5The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) TrialCohort Study · 2007 · 337 citations