What is the clinical evidence from this study?

Study design: Observational. Population: Pulmonary embolism (n=216). Intervention: Multi-detector row helical computed tomography (CT). Primary outcome: Proportion of diagnostic studies.

What question did this study set out to answer?

The aim is to evaluate the effectiveness of multi-detector row CT in diagnosing pulmonary embolism.

January 1, 2005Radiology

Diagnosing Pulmonary Embolism with Four–Detector Row Helical CT: Prospective Evaluation of 216 Outpatients and Inpatients

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Key result

Multi-detector row helical CT enabled diagnosis of pulmonary embolism in 91% of cases, with a 3-month thromboembolic event rate of 1.8% (95% CI: 0.2%-6.4%) after negative results.

Why the study?

Does multi-detector row helical CT provide a high proportion of diagnostic studies for pulmonary embolism in outpatients and inpatients?

Population

216 outpatients and inpatients, 101 male and 115 female.

Design

Cohort, Interpreted first in the emergency setting and subsequently by two…

Follow-up

3 months

Authors

MRMarie‐Pierre RevelInserm DPDavid PetroverUniversité Paris Cité AHA. HernigouAssistance Publique – Hôpitaux de Paris

Discussion

Member takes

Implication

May aid PE evaluation in mixed settings; leaves open need for randomized confirmation before practice change.

Key Points

The aim is to evaluate the effectiveness of multi-detector row CT in diagnosing pulmonary embolism.
Assessed 220 consecutive CT angiography studies in hospitalized and outpatient individuals.
Combined thoracic CT angiography and CT venography in patients over 40 years.
Used kappa statistic to measure agreement and chi-squared test for proportion comparison.
Good concordance between readings (kappa = 0.88; 95% CI: 0.77, 0.98).
Pulmonary embolism diagnosed in 54 (24.5%) cases; 15% had subsegmental PE.
3-month thromboembolic event rate after negative results was low at 1.8% (95% CI: 0.2%, 6.4%).

Study Design

Type

Observational (n=216)

Structured PICO

Does multi-detector row helical CT provide a high proportion of diagnostic studies for pulmonary embolism in outpatients and inpatients?

Population

216 outpatients and inpatients (220 consecutive CT angiography studies, 56% inpatients), 101 male (median age 66) and 115 female (median age 67).

Intervention

Multi-detector row helical CT (thoracic CT angiography with contiguous 1.25-mm sections, combined with CT venography in patients >40 years)

Outcome

Proportion of diagnostic studies and frequency of subsegmental and chronic PEsurrogate

Multi-detector row CT is highly diagnostic for pulmonary embolism, yielding diagnostic images in 91% of cases and a low 3-month thromboembolic event rate following a negative scan.

Cite This Study

Revel et al. (2005) conducted an observational in Pulmonary embolism (n=216). Multi-detector row helical computed tomography (CT) was evaluated on Proportion of diagnostic studies. Multi-detector row helical CT enabled diagnosis of pulmonary embolism in 91% of cases, with a 3-month thromboembolic event rate of 1.8% (95% CI: 0.2%-6.4%) after negative results.

synapsesocial.com/papers/6a10bc4b497e609eda6448d2 https://doi.org/10.1148/radiol.2341031880

Topics

Pulmonary embolism

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Diagnosing Pulmonary Embolism with Four–Detector Row Helical CT: Prospective Evaluation of 216 Outpatients and Inpatients

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Diagnosing Pulmonary Embolism with Four–Detector Row Helical CT: Prospective Evaluation of 216 Outpatients and Inpatients

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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