June 1, 1998The Journal of Nervous and Mental Disease
Remission and Relapse in Schizophrenia: The Madras Longitudinal Study
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Discussion
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Implication
Longitudinal study characterizes remission and relapse outcomes in first-onset schizophrenia, indicating predictive symptoms.
Key Points
- The aim is to characterize the course of remission and relapse in first-onset schizophrenia patients using monthly symptom data.
- Data collected monthly from 90 first-onset schizophrenics in Madras, India.
- Symptoms assessed using the Present State Exam to predict remission and relapse outcomes.
- Focus on differences between early and later episodes of schizophrenia.
- Remission from the first episode occurs in about 6 months; later episodes show remission at about 3 months.
- Hypomania and simple depression predict early remission from the first episode.
- Flat affect and grandiose delusions are associated with longer episodes and shorter remissions later.
Cite This Study
Eaton et al. (1998) studied this question.