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April 19, 2012Diabetes CareOpen Access

Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach

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Authors

Silvio E. InzucchiSilvio E. InzucchiUniversity of VermontRBRichard M. BergenstalHealthPartnersJohn B. BuseJohn B. BuseHigh Point University

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Implication

Clinical guidance outlines individualized glucose-lowering options in type 2 diabetes mellitus, highlighting cellular mechanisms to optimize treatment.

Key Points

  • To provide a patient-centered framework for selecting appropriate glucose-lowering therapies based on drug properties and cellular mechanisms.
  • Reviewed and categorized currently available glucose-lowering drug classes and specific compounds.
  • Assessed underlying cellular mechanisms and clinical characteristics to guide personalized agent selection.
  • Different classes of glucose-lowering agents exert glycemic control through distinct cellular targets and biological pathways.
  • Treatment strategies require aligning individual patient profiles and comorbidities with drug-specific mechanisms and potential adverse effects.

Cite This Study

Inzucchi et al. (2012) studied this question.

synapsesocial.com/papers/6a10c26249545a83bbee4e2dhttps://doi.org/10.2337/dc12-0413
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