Key result
Metabolic syndrome, driven primarily by obesity and insulin resistance, is a prevalent cluster of clinical disorders that significantly increases the risk of atherosclerotic cardiovascular disease.
Design
Review
Authors
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Affirms metabolic syndrome as key ASCVD risk driver; leaves open optimal therapeutic targets beyond lifestyle measures.
This review summarizes the clinical and molecular aspects of metabolic syndrome, highlighting the central role of obesity and insulin resistance in driving cardiovascular risk.
Moller et al. (2004) conducted a review in Metabolic syndrome. Metabolic syndrome, driven primarily by obesity and insulin resistance, is a prevalent cluster of clinical disorders that significantly increases the risk of atherosclerotic cardiovascular disease.
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