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February 1, 2026Vascular Health and Risk ManagementOpen Access

Coronary Artery Disease Risk Assessment by Coronary Artery Calcium Scoring in Asymptomatic Thai People with Diabetes Mellitus

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Key result

CAC scoring in asymptomatic diabetes influences management, increasing ABC target achievement to ~56% for CAC ≥100.

  • n=157

Why the study?

People with diabetes mellitus remain at high cardiovascular risk, but data were needed on the severity of coronary artery calcium, its correlation with cardiovascular risk scores, and the impact of testing on management in asymptomatic Thai patients.

Does coronary artery calcium scoring improve cardiovascular risk stratification and metabolic target attainment in asymptomatic Thai people with diabetes mellitus?

Population

Asymptomatic Thai people with diabetes mellitus

Comparison

Coronary artery calcium score ≥100 AU vs <100 AU

Follow-up

6 months

Authors

YTYotsapon ThewjitcharoenWCWaralee ChatchomchuanEWEkgaluck Wanothayaroj

Discussion

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Member takes

Overview

May support CAC-guided intensification in asymptomatic diabetes; leaves open outcome benefits without randomized data.

Study Design

Type

Cohort (n=157)

Multicenter

No

Structured PICO

Does coronary artery calcium scoring improve cardiovascular risk stratification and metabolic target attainment in asymptomatic Thai people with diabetes mellitus?

P
Population
Asymptomatic Thai people with diabetes mellitus
I
Intervention
Coronary artery calcium (CAC) scoring
O
Outcome
Severity of CAC, correlation of CAC risk scoring with different CV risk scores, and impacts of CAC testing on patient management (ABC control at 6 months)surrogate

Main Result

Absolute Event Rate: 55.7% vs 56.4%

CAC scoring in asymptomatic Thai patients with diabetes reveals a high prevalence of subclinical coronary atherosclerosis and is associated with improved attainment of metabolic targets at 6 months.

Limitations

  • Retrospective analysis with inherent biases
  • Small cohort size due to incomplete data
  • Short-term follow-up period
  • Confounding factors such as financial capability in a private setting
  • No comparison with age-matched patients who did not undergo CAC measurements

Cite This Study

Thewjitcharoen et al. (2026) conducted a cohort in Asymptomatic Diabetes Mellitus (n=157). Coronary Artery Calcium (CAC) scoring ≥100 AU vs. CAC <100 AU was evaluated on Achieved ABC target (A1C, blood pressure, and LDL cholesterol) at 6 months. Coronary artery calcium scoring in asymptomatic Thai patients with diabetes influenced clinical management, increasing achieved ABC metabolic targets to 55.7% at 6 months in those with CAC ≥100 AU.

synapsesocial.com/papers/6a10c4cdba20d9a181ee452ahttps://doi.org/10.2147/vhrm.s582744
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Potential Implications of Coronary Artery Calcium Testing for Guiding Aspirin Use Among Asymptomatic Individuals With Diabetes2012 · 51 citations
  2. 2Warranty Period of Zero Coronary Artery Calcium Score for Predicting All-Cause Mortality According to Cardiac Risk Burden in Asymptomatic Korean Adults2016 · 26 citations
  3. 3Contemporary use of coronary artery calcium for the allocation of aspirin in light of the 2022 USPSTF guideline recommendations2022 · 10 citations
  4. 4Improvements in risk stratification for the occurrence of cardiovascular disease by imaging subclinical atherosclerosis: a systematic review2011 · 415 citations
  5. 5Coronary Artery Calcium Score for Long-term Risk Classification in Individuals With Type 2 Diabetes and Metabolic Syndrome From the Multi-Ethnic Study of Atherosclerosis2017 · 205 citations