Key result
Calcium channel blockers linked to the highest sexual dysfunction rate at ~20% among hypertensive men.
Why the study?
Antihypertensive medications can cause deleterious adverse effects on sexual functions in hypertensive adult male patients, which may limit drug adherence and compliance.
Do different classes of antihypertensive medications affect sexual functions differently in hypertensive adult male patients?
Observational (n=159)
No
Do different classes of antihypertensive medications affect sexual functions differently in hypertensive adult male patients?
In a cohort of Nigerian hypertensive men, calcium channel blockers were associated with the highest occurrence of sexual dysfunction compared to other antihypertensive classes.
Antihypertensive choice may warrant sexual-function counseling; leaves open causal effects and need for randomized confirmation.
BACKGROUND: The potential for antihypertensive medications to produce deleterious adverse effects on sexual functions among hypertensive adult male patients has been widely reported, such adverse effects may limit drug adherence and compliance. AIM: The aim of this study was to assess the effect of antihypertensive medication use on sexual functions among hypertensive adult male patients. METHODOLOGY: The study was carried out at the outpatient clinic of a Nigerian University Teaching Hospital. A total of one hundred and fifty-nine recruited hypertensive adult male patients that were being managed at the center over a 3-month period between January 2017 and April 2017 participated in the study; provided they satisfied the inclusion and exclusion criteria for enrolment. RESULTS: The respondents were between 30 and 98 years of age, (mean of 59 ± 11.1 years). Blood pressure recorded was during their initial medical diagnosis for hypertension. Systolic blood pressure recorded was between 128 and 194 mmHg (mean of 162 ± 16.4 mmHg), while their diastolic blood pressure was between 78 and 120 mmHg (mean of 95 ± 10.7 mmHg). The highest occurrence of sexual dysfunctions was associated with calcium-channel blockers in 32 (20.1%) patients, followed by diuretics in 27 (17.0%) and, angiotensin-converting enzyme inhibitors in 20 (12.6%) patients. CONCLUSION: Calcium channel blockers caused the highest occurrence of sexual dysfunctions.
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Akinyede et al. (2020) conducted an observational in Hypertension (n=159). Antihypertensive medications was evaluated on Occurrence of sexual dysfunctions. Calcium channel blockers were associated with the highest occurrence of sexual dysfunctions (20.1%), followed by diuretics (17.0%) and ACE inhibitors (12.6%) in hypertensive adult males.
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