Why the study?
What is the natural history and appropriate indication for operation in patients with congenital valvar aortic stenosis?
Population
218 patients with congenital valvar aortic stenosis aged between 1 and 25 years at presentation
Design
Cohort
Follow-up
1 to 26 years (average 8.7 years)
Authors
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Long-term data support monitoring mild congenital aortic stenosis; leaves optimal intervention timing unresolved.
What is the natural history and appropriate indication for operation in patients with congenital valvar aortic stenosis?
Clinical assessment is reliable for determining the severity of congenital valvar aortic stenosis, and operation is indicated for moderate or severe stenosis with restrictive symptoms or ECG changes, rather than based on routine catheterization gradients.
Hossack et al. (1980) studied this question.
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