Key result
Diabetes was independently associated with higher 30-day mortality after UA/NSTEMI (OR 1.78; 95% CI 1.24-2.56) and STEMI (OR 1.40; 95% CI 1.24-1.57) compared to patients without diabetes.
Why the study?
Does the presence of diabetes mellitus increase mortality at 30 days and 1 year in patients with acute coronary syndromes?
Observational (n=62,036)
Yes
Does the presence of diabetes mellitus increase mortality at 30 days and 1 year in patients with acute coronary syndromes?
Effect estimate: OR 1.40 (95% CI 1.24-1.57)
Absolute Event Rate: 8.5% vs 5.4%
p-value: p=<0.001
Diabetes is an independent predictor of higher 30-day and 1-year mortality in patients presenting with acute coronary syndromes, regardless of whether they present with STEMI or UA/NSTEMI.
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Diabetes signals higher early ACS mortality risk warranting closer monitoring; confirms diabetes as independent prognostic factor in meta-analyzed data.
Donahoe et al. (2007) conducted an observational in Acute Coronary Syndromes (n=62,036). Diabetes mellitus vs. No diabetes was evaluated on Mortality at 30 days following STEMI (OR 1.40, 95% CI 1.24-1.57, p=<0.001). Diabetes was independently associated with higher 30-day mortality after UA/NSTEMI (OR 1.78; 95% CI 1.24-2.56) and STEMI (OR 1.40; 95% CI 1.24-1.57) compared to patients without diabetes.
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