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May 15, 2023Journal of the American Heart AssociationOpen Access

Diabetes was associated with a 52% higher hazard of all-cause 1-year mortality (HR 1.52; 95% CI 1.23-1.89) in patients hospitalized with acute myocardial infarction.

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Why the study?

Does diabetes increase the risk of mortality and affect clinical management in patients hospitalized with acute myocardial infarction?

Population

21 094 weighted hospitalizations for AMI across 4 US communities

Comparison

Patients with diabetes vs patients without diabetes

Design

Community surveillance study

Follow-up

1 year

Key result

Diabetes was associated with a 52% higher hazard of all-cause 1-year mortality (HR 1.52; 95% CI 1.23-1.89) in patients hospitalized with acute myocardial infarction.

Authors

VJVardhmaan JainAQArman QamarKMKunihiro Matsushita

Discussion

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Member takes

Overview

Diabetes signals excess post-AMI mortality amid treatment gaps; leaves open whether closing disparities improves survival.

Study Design

Type

Observational (n=21,094)

Multicenter

Yes

Structured PICO

Does diabetes increase the risk of mortality and affect clinical management in patients hospitalized with acute myocardial infarction?

P
Population
21,094 weighted hospitalizations for acute myocardial infarction across 4 US communities from 2000 to 2014, evaluated for the impact of diabetes on clinical management and 1-year mortality.
E
Exposure
Diabetes mellitus (exposure)
C
Comparator
No diabetes mellitus
O
Outcome
All-cause 1-year mortalityhard clinical

Main Result

Hazard Ratio: 1.52 (95% CI 1.23–1.89)

In patients hospitalized with AMI, diabetes is associated with less typical presentations, lower use of evidence-based therapies, and a significantly higher risk of 1-year mortality.

Cite This Study

Jain et al. (2023) conducted an observational in Acute Myocardial Infarction (n=21,094). Diabetes vs. No diabetes was evaluated on All-cause 1-year mortality (HR 1.52, 95% CI 1.23-1.89). Diabetes was associated with a 52% higher hazard of all-cause 1-year mortality (HR 1.52; 95% CI 1.23-1.89) in patients hospitalized with acute myocardial infarction.

synapsesocial.com/papers/6a5cf6c8a4cd7c4850034d66https://doi.org/10.1161/jaha.122.028923
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