Key result
LAA exclusion during AF ablation and mitral surgery fails to improve 2-year freedom from AF.
Why the study?
Does left atrial appendage exclusion improve freedom from atrial fibrillation in patients undergoing mitral valve surgery and surgical radiofrequency ablation?
Population
100 patients who underwent MVS and AFSA
Comparison
LAA exclusion vs no LAA exclusion
Design
Retrospective single-center cohort study
Follow-up
2 years
Authors
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LAA exclusion should not yet change practice for sinus rhythm maintenance; hypothesis-generating for smaller left atria.
Cohort (n=100)
No
Does left atrial appendage exclusion improve freedom from atrial fibrillation in patients undergoing mitral valve surgery and surgical radiofrequency ablation?
Absolute Event Rate: 84.6% vs 75%
p-value: p=0.230
Left atrial appendage exclusion during mitral valve surgery and AF ablation does not significantly improve overall sinus rhythm maintenance at 2 years, but provides significant rhythm benefit in patients with smaller left atrial dimensions (≤ 6 cm).
Lavalle et al. (2021) conducted a cohort in Atrial fibrillation undergoing mitral valve surgery (n=100). Left atrial appendage exclusion vs. No left atrial appendage exclusion was evaluated on Freedom from atrial fibrillation at 2-year follow-up (p=0.230). Left atrial appendage exclusion during atrial fibrillation ablation and mitral valve surgery did not significantly improve freedom from AF at 2 years compared to no exclusion (84.6% vs 75%; p=0.230).
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