Key result
Guillain-Barré syndrome recovery linked to reversible Takotsubo cardiomyopathy as a rare dysautonomic complication.
Why the study?
Takotsubo cardiomyopathy is a life-threatening manifestation of dysautonomia in patients with Guillain-Barre syndrome that is not widely underlined, with few reported cases.
Case Report (n=1)
Highlights Takotsubo cardiomyopathy as a rare, life-threatening manifestation of dysautonomia in patients recovering from Guillain-Barré syndrome.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to Takotsubo cardiomyopathy in Guillain-Barré recovery; leaves open whether this link is causal or coincidental.
Dysautonomia is a common and severe complication of Guillain-Barré syndrome (GBS), which may manifest as cardiac arrhythmias, labile blood pressure, diaphoresis, and changes in gastrointestinal motility. Takotsubo cardiomyopathy (TCM) is a life-threatening manifestation of dysautonomia in patients with GBS, which is not widely underlined in the literature. The association between GBS and TCM has been well-documented in previous studies; however, there are few reported cases with GBS who developed TCM following their diagnosis with GBS. In this case report, we will discuss our experience treating a 59-year-old female patient who became hemodynamically unstable while recovering from an acute GBS infection. She was diagnosed with TCM after undergoing an echocardiogram and coronary angiogram ruling out thrombotic or obstructive coronary disease and myocarditis.
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Mohamed et al. (2023) conducted a case report in Guillain-Barré syndrome complicated by Takotsubo cardiomyopathy (n=1). Intravenous immunoglobulin, plasmapheresis, and vasoactive support was evaluated. A 59-year-old female recovering from Guillain-Barré syndrome developed Takotsubo cardiomyopathy, a rare and life-threatening manifestation of dysautonomia, which resolved with medical management.
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