Why the study?
The association between Guillain-Barré syndrome and takotsubo cardiomyopathy is rarely described.
Highlights a rare association between Guillain-Barré syndrome and takotsubo cardiomyopathy, suggesting a potential role for routine echocardiographic screening in these patients.
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Association in one case; leaves open whether screening or mechanistic studies are warranted in Guillain-Barré syndrome.
A 41-year-old woman was admitted with progressive paraesthesia and weakness and was diagnosed with Guillain-Barré syndrome. Following an initial period of recovery with intravenous immunoglobulin treatment, she developed acute chest pain associated with electrocardiographic changes. Investigations excluded acute coronary syndrome and instead confirmed a diagnosis of takotsubo cardiomyopathy, which was treated medically. The patient made an excellent neurological and cardiac recovery. Here we discuss the rarely described association between these two conditions and suggest that patients admitted with Guillain-Barré syndrome may benefit from routine screening with echocardiography.
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Jones et al. (2020) studied this question.
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