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October 17, 2012Clinical Psychological ScienceOpen Access

Key Characteristics of Major Depressive Disorder Occurring in Childhood, Adolescence, Emerging Adulthood, and Adulthood

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Authors

PRPaul RohdeOregon Research InstitutePLPeter M. LewinsohnWesleyan UniversityDKDaniel N. KleinNorthern Illinois University

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Implication

Cohort study reveals shifting depression incidence and suicide risk across age stages, highlighting peak vulnerability in emerging adulthood and adolescence.

Key Points

  • To compare the incidence, recurrence, duration, comorbidity, and suicide attempt patterns of major depressive disorder across four key developmental stages.
  • Longitudinal cohort analysis of 816 participants (56% female, 89% White) from the Oregon Adolescent Depression Project.
  • Evaluated psychiatric outcomes across four developmental periods: Childhood (ages 5–12.9), Adolescence (ages 13–17.9), Emerging Adulthood (ages 18–23.9), and Adulthood (ages 24–30).
  • Cumulative MDD incidence reached 51%, with first-onset incidence lowest in childhood and higher in emerging adulthood than adulthood.
  • Childhood depressive episodes exhibited greater duration than later periods, while recurrence rates were lower in childhood and comparable across subsequent periods.
  • Female sex predicted first incident MDD across all four developmental periods, while suicide attempt rates were significantly higher in adolescence than in emerging adulthood or adulthood.

Cite This Study

Rohde et al. (2012) studied this question.

synapsesocial.com/papers/6a10ef3669716c70d0488f1ahttps://doi.org/10.1177/2167702612457599
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Psychosocial functioning of young adults who have experienced and recovered from major depressive disorder during adolescence.2003 · 271 citations
  2. 2The prevalence and co-morbidity of subthreshold psychiatric conditions2004 · 253 citations
  3. 3Psychosocial risk factors for future adolescent suicide attempts.1994 · 561 citations