Key result
Planned RCT evaluates QSTMAS herbal paste for depression and anxiety in coronary heart disease.
Why the study?
Psycho-cardiology diseases aggravate CHD progression, but antidepressant adverse effects necessitate safe and effective early intervention methods.
Population
99 CHD patients with Qi deficiency and blood stasis syndrome combined with depression and/or anxiety
Comparison
Standard western medicine plus QSTMAS herbal paste vs standard western medicine alone
Design
Single-blind, single-center, randomized controlled trial protocol
Follow-up
12 weeks
Authors
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Does not yet support clinical use of QSTMAS in coronary heart disease; upcoming RCT will extend evidence on herbal effects on mood.
RCT (n=99)
Single-blind
1:2 ratio
No
Chen et al. (2023) conducted an RCT in Coronary heart disease with depression and/or anxiety (n=99). QSTMAS herbal paste vs. Standard western medicine treatment was evaluated on Changes in GAD-7 and PHQ-9 scores. QSTMAS herbal paste will be evaluated in a planned 99-patient randomized controlled trial to determine its effect on depression and anxiety scores in patients with coronary heart disease.
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