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October 15, 2012China Journal of Chinese Materia Medica

Study on clinical intervention of Jiawei Shengdan Louxie Sini Fang on coronary heart disease with depression

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Key result

Jiawei Shengdan Louxie Sini Fang improved angina, syndrome curative effect, and HAMA rating scale compared to fluoxetine in patients with coronary heart disease and depression.

Why the study?

Does Jiawei Shengdan Louxie Sini Fang improve angina and depression symptoms in patients with coronary heart disease, stable angina, and depression compared to fluoxetine?

Population

Patients with coronary heart disease, stable angina, and depression

Comparison

Jiawei Shengdan Louxie Sini Fang added to basic… vs Fluoxetine added to basic western medicine…

Design

RCT, randomized

Authors

LZLanfeng Zhang

Discussion

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Overview

Supports TCM option over fluoxetine for CHD with depression; extends RCT evidence for herbal formulations in comorbid conditions.

Study Design

Type

RCT

Randomization

randomized

Structured PICO

Does Jiawei Shengdan Louxie Sini Fang improve angina and depression symptoms in patients with coronary heart disease, stable angina, and depression compared to fluoxetine?

P
Population
Patients with coronary heart disease, stable angina, and depression.
I
Intervention
Jiawei Shengdan Louxie Sini Fang added to basic western medicine treatment for coronary heart disease
C
Comparator
Fluoxetine added to basic western medicine treatment for coronary heart disease
O
Outcome
Angina curative effect, syndrome curative effect, and HAMA rating scalepatient reported

Jiawei Shengdan Louxie Sini Fang may improve angina and anxiety/depression symptoms in patients with coronary heart disease and comorbid depression compared to fluoxetine.

Cite This Study

Lanfeng Zhang (2012) conducted an RCT in Coronary heart disease with stable angina and depression. Jiawei Shengdan Louxie Sini Fang vs. Fluoxetine was evaluated on Angina curative effect, syndrome curative effect and HAMA rating scale. Jiawei Shengdan Louxie Sini Fang improved angina, syndrome curative effect, and HAMA rating scale compared to fluoxetine in patients with coronary heart disease and depression.

synapsesocial.com/papers/6a99475108ab6325d2e1324ehttps://doi.org/10.4268/cjcmm20122030
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression2024 · 6 citations
  2. 2Qi-Regulating and Blood Circulation-Promoting Therapy Improves Health Status of Stable Angina Pectoris Patients with Depressive Symptoms2021 · 13 citations
  3. 3The effect of Qi‐Shao‐Tong‐Mai‐An‐Shen herbal paste on coronary heart disease patients with depression and/or anxiety: Study protocol for a randomized controlled trial2024
  4. 4The Effect of Qi-Shao-Tong-Mai-An-Shen (QSTMAS) Herbal Paste in Coronary Heart Disease Patients with Depression and/or Anxiety: A Randomized Controlled Clinical Trial Protocol2023
  5. 5The Influencing Factors and Traditional Chinese Medicine Syndrome Characteristics of Depression/Anxiety in Patients with Coronary Heart Disease: A Cross-sectional Study2024 · 2 citations