Key result
Xuefu Zhuyu granule significantly improved chest stuffiness and heartache syndrome in stable angina patients with depressive symptoms (efficacy index 61.24%, P<0.05 vs baseline).
Why the study?
Depressive symptoms are prevalent in coronary heart disease and reduce quality of life, but psychotropic drugs carry warnings about side effects, creating an urgent need for safer alternatives.
Does Xuefu Zhuyu granule improve angina pectoris-specific health status in patients with stable angina pectoris and depressive symptoms?
Population
30 patients with stable angina pectoris stratified by depressive symptoms
Comparison
Xuefu Zhuyu decoction/granule evaluated across baseline depressive symptom strata
Design
Prospective trial
Follow-up
12 weeks
Authors
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May support adjunctive use in stable angina with depression; leaves open confirmation by randomized trials.
Does Xuefu Zhuyu granule improve angina pectoris-specific health status in patients with stable angina pectoris and depressive symptoms?
p-value: p=< 0.05
Xuefu Zhuyu granule may improve angina-specific health status and serum ATP levels in patients with stable angina and depressive symptoms.
Wang et al. (2021) studied Stable angina pectoris with depressive symptoms (n=30). Xuefu Zhuyu granule vs. Baseline was evaluated on Chest stuffiness and heartache syndrome (p=< 0.05). Xuefu Zhuyu granule significantly improved chest stuffiness and heartache syndrome in stable angina patients with depressive symptoms (efficacy index 61.24%, P<0.05 vs baseline).
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