Key result
In untreated essential hypertension, age (beta=0.204, P<0.0001), LDL cholesterol (beta=0.113, P=0.004), and night-time BP (beta=0.101, P=0.009) were independent correlates of relative wall thickness.
Why the study?
How do different left ventricular geometric patterns correlate with ambulatory blood pressure and extra-cardiac organ damage in untreated essential hypertension?
Population
669 untreated essential hypertensives
Comparison
Categorization by left ventricular geometric… vs Comparison between different LV geometric patterns
Design
Cross-sectional
Authors
Loading...
Night-time BP and LDL associate with concentric remodeling in untreated hypertension; hypothesis-generating, should not yet change practice.
Cross-Sectional (n=669)
How do different left ventricular geometric patterns correlate with ambulatory blood pressure and extra-cardiac organ damage in untreated essential hypertension?
Left ventricular geometric patterns reflect different degrees of blood pressure load and subclinical extra-cardiac alterations, serving as reliable markers of cardiovascular risk.
Cuspidi et al. (2010) conducted a cross-sectional in untreated essential hypertension (n=669). Left ventricular geometric patterns was evaluated on Relationship between LV geometry, ambulatory BP and markers of vascular and renal organ damage. In untreated essential hypertension, age (beta=0.204, P<0.0001), LDL cholesterol (beta=0.113, P=0.004), and night-time BP (beta=0.101, P=0.009) were independent correlates of relative wall thickness.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: