Key result
Carotid artery imaging was more strongly associated with the 10-year ASCVD score than coronary artery imaging, showing a lower bias between true and predicted scores (0.37% vs 2.07% and 2.47%).
Why the study?
It was unknown whether coronary or carotid artery imaging shows the strongest association with the atherosclerotic cardiovascular disease (ASCVD) score.
Does carotid artery imaging predict the 10-year ASCVD score more accurately than coronary artery imaging in patients undergoing CTA?
Observational (n=220)
Does carotid artery imaging predict the 10-year ASCVD score more accurately than coronary artery imaging in patients undergoing CTA?
Absolute Event Rate: 0.37% vs 2.07%
Carotid artery imaging features demonstrate a stronger association with the calculated 10-year ASCVD risk score than coronary artery imaging features.
Carotid features on CTA should not yet alter ASCVD risk stratification; supports further validation in prospective cohorts.
PURPOSE: The aim of this study was to compare coronary and carotid artery imaging and determine which one shows the strongest association with atherosclerotic cardiovascular disease (ASCVD) score. PATIENTS AND METHODS: Two separate series patients who underwent either coronary computed tomography angiography (CTA) or carotid CTA were included. We recorded the ASCVD scores and assessed the CTA imaging. Two thirds were used to build predictive models, and the remaining one third generated predicted ASCVD scores. The Bland-Altman analysis analyzed the concordance. RESULTS: A total of 110 patients were included in each group. There was no significant difference between clinical characteristics. Three imaging variables were included in the carotid model. Two coronary models (presence of calcium or Agatston score) were created. The bias between true and predicted ASCVD scores was 0.37 ± 5.72% on the carotid model, and 2.07 ± 7.18% and 2.47 ± 7.82% on coronary artery models, respectively. CONCLUSIONS: Both carotid and coronary artery imaging features can predict ASCVD score. The carotid artery was more associated to the ASCVD score than the coronary artery.
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Li et al. (2019) conducted an observational in Atherosclerotic cardiovascular disease (ASCVD) risk assessment (n=220). Carotid CTA vs. Coronary CTA was evaluated on Bias between true and predicted ASCVD scores. Carotid artery imaging was more strongly associated with the 10-year ASCVD score than coronary artery imaging, showing a lower bias between true and predicted scores (0.37% vs 2.07% and 2.47%).
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