Why the study?
Does the 10-year ASCVD risk score accurately predict coronary artery stenosis and plaque thickness on computed tomography angiography?
Does the 10-year ASCVD risk score accurately predict coronary artery stenosis and plaque thickness on computed tomography angiography?
While higher 10-year ASCVD risk scores correlate with increased coronary stenosis and plaque thickness on CCTA, there is significant discordance, highlighting the limitations of clinical risk scores in predicting individual anatomical disease.
Elevated ASCVD scores associate with more coronary stenosis and plaque on CCTA; discordance leaves individual predictive accuracy open.
OBJECTIVE: The aim of this study was to characterize the relationship between computed tomography angiography imaging characteristics of coronary artery and atherosclerotic cardiovascular disease (ASCVD) score. METHODS: We retrospectively identified all patients who underwent a coronary computed tomography angiography at our institution from December 2013 to July 2016, then we calculated the 10-year ASCVD score. We characterized the relationship between coronary artery imaging findings and ASCVD risk score. RESULTS: One hundred fifty-one patients met our inclusion criteria. Patients with a 10-year ASCVD score of 7.5% or greater had significantly more arterial segments showing stenosis (46.4%, P = 0.008) and significantly higher maximal plaque thickness (1.25 vs 0.53, P = 0.001). However, among 56 patients with a 10-year ASCVD score of 7.5% or greater, 30 (53.6%) had no arterial stenosis. Furthermore, among the patients with a 10-year ASCVD score of less than 7.5%, 24 (25.3%) had some arterial stenosis. CONCLUSIONS: There is some concordance but not a perfect overlap between 10-year ASCVD risk scores and coronary artery imaging findings.
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Li et al. (2018) studied this question.
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