Key result
Measurement of the coronary artery calcium score, combined with traditional risk factors, provides a strong predictive model for 10-year cardiovascular risk to guide preventative therapies.
Why the study?
Does coronary artery calcium scoring combined with traditional risk factors improve cardiovascular risk prediction in asymptomatic patients?
Does coronary artery calcium scoring combined with traditional risk factors improve cardiovascular risk prediction in asymptomatic patients?
Coronary artery calcium scoring combined with traditional risk factors is a valuable tool for assessing 10-year cardiovascular risk and guiding preventive therapies in asymptomatic intermediate-risk patients.
May aid risk stratification in asymptomatic patients; leaves open prospective trials to confirm outcome benefit.
As coronary artery calcium (CAC) is atherosclerosis and not just a marker of cardiovascular (CV) disease, measurement of a patient's coronary artery calcium score (CACS) is a strong predictor of risk. Clinically performed in asymptomatic patients, the CACS, along with several CV risk factors, namely age, sex, ethnicity, diabetes, tobacco use, family history, cholesterol level, blood pressure, and use of cholesterol or hypertensive medications, provide a predictive model of 10 year risk for CV events. A smartphone "App" makes this quick to obtain and use. This helps the clinician in making recommendations for both lifestyle changes and statin therapy. Those patients in which the most benefit occur from measurement of a CACS are those at an intermediate CV risk. Measurement of the CACS has become an integral part of the clinician's assessment of a patient's CV risk and for guiding preventative therapies.
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Kerut et al. (2018) conducted a review in Cardiovascular disease risk. Coronary artery calcium score (CACS) was evaluated on 10 year risk for CV events. Measurement of the coronary artery calcium score, combined with traditional risk factors, provides a strong predictive model for 10-year cardiovascular risk to guide preventative therapies.
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