Patients with primary disorders of impaired wakefulness exhibit adrenergic hyperactivity and a high prevalence of mitral valve prolapse, which may explain associated fatigue and difficulties with stimulant treatments.
Authors
No takes yet. Share an insight, caveat, or question.
Adrenergic hyperactivity and mitral valve prolapse may underlie symptoms in sleep apnea; leaves open causal links and need for prospective studies.
Clark et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: