Why the study?
Is there a difference in the urinary excretion of catecholamines and their derivatives between patients with primary hypertension and normotensive subjects?
Population
42 male subjects studied under in-patient conditions.
Design
Case-control
Authors
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No support for catecholamine excess in primary hypertension; hypothesis-generating and should not yet change practice.
Is there a difference in the urinary excretion of catecholamines and their derivatives between patients with primary hypertension and normotensive subjects?
The study found no evidence of increased urinary catecholamine excretion in essential hypertension, challenging the concept that excessive circulating catecholamines are responsible for elevated blood pressure in these patients.
Bing et al. (1977) studied this question.
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