Key result
A high lipid-like component on B-mode imaging predicted future atherothrombotic cerebral infarction in patients with asymptomatic carotid stenosis (HR 4.4; p<0.05).
Why the study?
Does computer-assisted analysis of plaque heterogeneity on B-mode imaging predict atherothrombotic cerebral infarction in patients with asymptomatic carotid stenosis?
Population
250 patients with 297 asymptomatic plaques causing 40-99% carotid artery stenosis
Design
Cohort
Follow-up
22 +/- 15 months
Authors
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May aid risk stratification in asymptomatic carotid stenosis; leaves open whether plaque analysis improves outcomes.
Cohort (n=250)
Does computer-assisted analysis of plaque heterogeneity on B-mode imaging predict atherothrombotic cerebral infarction in patients with asymptomatic carotid stenosis?
Effect estimate: HR 4.4
p-value: p=<0.05
Computer-assisted analysis of plaque heterogeneity on B-mode ultrasound can predict the risk of future cerebral infarction in patients with asymptomatic carotid stenosis.
Hashimoto et al. (2009) conducted a cohort in Asymptomatic carotid artery stenosis (n=250). Computer-assisted analysis of plaque heterogeneity (lipid-like echogenicity) was evaluated on Atherothrombotic cerebral infarction due to carotid stenosis (HR 4.4, p=<0.05). A high lipid-like component on B-mode imaging predicted future atherothrombotic cerebral infarction in patients with asymptomatic carotid stenosis (HR 4.4; p<0.05).
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