What question did this study set out to answer?

This study aims to evaluate the relationship between serum apolipoprotein AI concentrations and the risk of developing coronary heart disease.

The Tromsø Heart Study: Serum apolipoprotein Al concentration in relation to future coronary heart disease

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Case-control study assesses apolipoprotein AI levels in relation to coronary heart disease, suggesting HDL cholesterol may be a stronger predictor.

This study aims to evaluate the relationship between serum apolipoprotein AI concentrations and the risk of developing coronary heart disease.
Measured apolipoprotein AI concentrations in serum using immunoelectrophoresis.
Compared concentrations between 12 subjects who developed coronary events and 16 matched control subjects.
Conducted discriminant function analysis to assess predictive power of apolipoprotein AI and HDL cholesterol.
Mean apolipoprotein AI concentration was significantly lower in cases compared to controls (exact values not provided).
No significant difference noted in the HDL cholesterol to apolipoprotein AI ratio between cases and controls.
Apolipoprotein AI concentration was a weaker predictor of coronary heart disease than HDL cholesterol in discriminant analysis.

Ishikawa et al. (1978) studied this question.

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Case-control study assesses apolipoprotein AI levels in relation to coronary heart disease, suggesting HDL cholesterol may be a stronger predictor.