What question did this study set out to answer?

To evaluate changes in serum lipids during exposure to an oral contraceptive combination of mestranol and norethynodrel over time.

Serum lipids during oral contraceptive exposure

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To evaluate changes in serum lipids during exposure to an oral contraceptive combination of mestranol and norethynodrel over time.
Participants took an oral contraceptive steroid combination for 6 to 60 months.
Serum total cholesterol, triglyceride levels, and alpha lipoprotein levels were measured at various time points.
Serum total cholesterol levels remained stable throughout the study period.
Alpha lipoprotein levels increased and stayed slightly elevated during the study.
Serum total triglycerides increased from the sixth to the eighteenth month of exposure.

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Randomized trial investigates serum lipid changes during oral contraceptive exposure, suggesting specific adjustments in lipid profiles.

Corredor et al. (1970) studied this question.

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